GINGEROL AND PARADOL.1
نویسندگان
چکیده
منابع مشابه
Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects.
BACKGROUND Ginger shows promising anticancer properties. No research has examined the pharmacokinetics of the ginger constituents 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in humans. We conducted a clinical trial with 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol, examining the pharmacokinetics and tolerability of these analytes and their conjugate metabolites. METHODS Human vol...
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Inspite of the large body of genomic data obtained from the transcriptome of Zingiber officinale, very few studies have focused on the identification and characterization of miRNAs in gingerol biosynthesis. Zingiber officinale transcriptome was analyzed using EST dataset (38169 total) deposited in public domains. In this paper computational functional annotation of the available ESTs and identi...
متن کاملGingerol Fraction from Zingiber officinale Protects Against Gentamicin-
26 Nephrotoxicity is the main complication of gentamicin (GM) treatment. GM induces 27 renal damage by overproduction of reactive oxygen species and inflammation in 28 proximal tubular cells. Phenolic compounds from ginger, called gingerols, have 29 demonstrated to have antioxidant and anti-inflammatory effects. We investigated if the 30 oral treatment with an enriched solution of gingerols (GF...
متن کاملImmunosuppressive activity of 8-gingerol on immune responses in mice.
8-gingerol is one of the principal components of ginger, which is widely used in China and elsewhere as a food, spice and herb. It shows immunosuppressive activity on the immune responses to ovalbumin (OVA) in mice. In the present study, we found that 8-gingerol suppressed lipopolysaccharide (LPS) and concanavalin A (ConA)-stimulated splenocyte proliferation in vitro. In vivo, 8-gingerol not on...
متن کاملGingerol fraction from Zingiber officinale protects against gentamicin-induced nephrotoxicity.
Nephrotoxicity is the main complication of gentamicin (GM) treatment. GM induces renal damage by overproduction of reactive oxygen species and inflammation in proximal tubular cells. Phenolic compounds from ginger, called gingerols, have been demonstrated to have antioxidant and anti-inflammatory effects. We investigated if oral treatment with an enriched solution of gingerols (GF) would promot...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 1917
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja02252a021